Endocrine Abstracts

Objectives: To determine the effect on bone mineral density (BMD) of the sub clinical hyperthyroidism (SH) due to TSH-suppressive treatment with levothyroxine after thyroidectomy in men with differentiated thyroid carcinoma (DTC).Materials and methods: Cross-sectional and retrospective study in 32 men (56±14 years) treated with levothyroxine for a minimum of 5 years, with TSH concentrations <0.05 mUI/ml and normal T3 levels in all determinations...

Introduction: Interferon-α (IFN-α) exerts different immune effects and is used in current therapy for chronic hepatitis C virus (HCV) infection. One of the side-effects of IFN-α therapy is interferon-induced thyroiditis (IIT). The role of lymphocyte subpopulations in IIT remains to be defined.Objective: This study was conducted to assess different peripheral blood lymphocyte subpopulations, mainly regulatory CD4+CD25+...

Introduction: Patients with type 1 diabetes mellitus (DM1) present a high prevalence of autoimmune associated diseases. Recently, we described a prevalence of latent pernicious anemia (LPA) of 12.4% in DM1.Objectives: A 5-year follow-up study of a cohort of DM1 patients in order to evaluate the evolution of biochemical markers of LPA, defined as a serum pepsinogen I (PI) concentration below normal limits.Material and methods: One h...